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ColoTect Non-Invasive Colorectal Cancer Screening
According to the World Health Organization, Colorectal cancer (CRC) is the third most common cancer type worldwide; in 2020,Almost 2 million cases were diagnosed.
Colorectal cancer is the second most common cause of cancer death, leading to almost 1 million deaths per year. This is even though effective screening techniques exist that could reduce the number of deaths from this disease.
Colorectal cancer (CRC) is the most preventable yet least prevented form of cancer. When caught in early stages, it is more treatable in 90% of people
ColoTect Approach
Convenient – Self-sampling at home with no special preparation needed.
ColoTect is a non-invasive, highly sensitive screening test for colorectal cancer (CRC) and precancerous lesions. Human DNA is extracted from stool sample self-collected at home by the patient and used for multiplex methylation specific PCR to detect abnormally methylated CRC marker genes——SDC2, ADHFE1, and PPP2R5C.
The second highest mortality
The third highest incidence
Risk of CRC increases dramatically after the age of 50 years
Screening is an important step in finding early stages of CRC that can be 90% cured when caught early
Self-sampling at home. No special prep or need for time off
Highly sensitive to find 87% CRC and 42.1% advanced adenoma
Specificity is as high as 93%
average-risk adults aged 45 to 75 years
*The NCCN guideline recommends a screening interval of every 3 years with stool DNA test.
American Cancer Society recommends starting regular screening at age 45.
Turnaround times for specific tests vary as per the table below. TATs are calculated from the time the sample is received and accepted at the laboratory.
| Product Name | Product Code | TAT |
|---|---|---|
| ColoTect Non-invasive Colorectal Cancer Screening | SDX2101 | 5 days |
Genalive Genetic Counselors are available to Healthcare providers to help navigate which test is best for their patient.
