Preimplantation Genetic Testing for Aneuploidy (PGT-A)
Preimplantation Genetic Testing for Monogenic Disorders (PGT-M)
Clinical Whole Exome Sequencing (cWES)
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Preimplantation Genetic Testing for Monogenetic Disorder (PGT-M)
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Pre-Preimplantation Genetic Testing for Monogenetic Disorder (PPGT-M)
Couples who have a known familial genetic mutation may still want to have children. They are often encouraged to use Invitro Fertilization (IVF) to achieve pregnancy.
During the IVF cycle a genetic test of the embryos called PGT-M, or preimplantation genetic testing for monogenetic disorder, can be used to test the presence of a genetic mutation known in the family. PGT-M can also provide chromosomal analysis for gender detection of the tested embryos.
Before PGT-M testing is arranged, a mandatory PPGT-M, or pre-preimplantation genetic testing for monogenetic disorder test, is used as a confirmation test for a couple with a known genetic disease who are planning to perform IVF
PGT-M at Genalive provides a wide range of genetic disease testing with benefits that include:
Identifying embryos carrying genetic mutations responsible for monogenic diseases before they are transferred to the uterus. This can help avoid the emotional and ethical challenges associated with terminating a pregnancy due to a genetic abnormality.
Prevention of having an abnormal baby with a genetic disease.
Detects many genetic diseases.
>97 % - depending on the mutation type.
A couple with a confirmed family history of genetic disease (re-confirmed with PPGT-M) and planning to do IVF cycle.
Turnaround times for specific tests vary as per the table below. TATs are calculated from the time the sample is received and accepted at the laboratory.
| Product Name | Product Code | TAT |
|---|---|---|
| Pre-Preimplantation Genetic Testing -Monogenetic disorder (PPGT-M) (Available Protocol) | SDX3201 | 7 days |
| Pre-Preimplantation Genetic Testing -Monogenetic disorder (PPGT-M) (New Protocol) | SDX3202 | 40-50 days |
| Pre-Preimplantation Genetic Testing -Monogenetic disorder (PPGT-M) (New Protocol + HLA typing) | SDX3203 | 40-50 days |
| Pre-Preimplantation Genetic Testing -Monogenetic disorder (PPGT-M) (Available Protocol + HLA typing) | SDX3204 | 7 days |
Genalive Genetic Counselors are available to healthcare providers to help navigate which test is best for their patient.
| Product Name | Product Code | TAT |
|---|---|---|
| Preimplantation Genetic Testing -Monogenetic disorder (PGT-M) (Frozen) | SDX3210 | 15 days |
| Rapid Preimplantation Genetic Testing -Monogenetic disorder (PGT-M) (Fresh) | SDX3211 | 48 hours |
| Preimplantation Genetic Testing -Monogenetic disorder (PGT-M) + HLA typing (Frozen) | SDX3212 | 15 days |
| Preimplantation Genetic Testing -Monogenetic disorder (PGT-M) + HLA typing (Fresh) | SDX3213 | 48 hours |
Genalive Genetic Counselors are available to healthcare providers to help navigate which test is best for their patient.
